One-stop Filling and Packaging Solutions for the Pharma & Healthcare Industry

TRPACK is ready to tackle any pharma & healthcare filling and packaging challenge!

 

  • In the pharmaceutical and healthcare industry, products such as liquid medicines, disinfectants, oral solutions and wound care products require high levels of precision, strict hygiene and regulatory compliance. Manufacturers face challenges including complex bottle types, frequent changeovers, contamination risks and rising labour costs.

  •  

    TRPACK provides advanced, automated pharmaceutical filling and packaging solutions, integrating bottle unscrambling, precise filling, capping, labelling and coding into a single, intelligent production line. With a sanitary design and stable control systems, our equipment ensures accurate filling, flexible operation and consistent product quality. 

  • Adopting TRPACK’s integrated healthcare packaging line enables manufacturers to reduce manual labour, minimize product waste, improve production efficiency and establish a scalable, sustainable production system for long-term growth in the global pharmaceutical and healthcare markets.

Applicable for various shapes and material container

We can provide solutions for these products.....

TRPACK Pharmaceutical industry applicable bottles

  • Oral Liquid Medicine
  • Cough Syrup
  • Vitamin Syrup
  • Herbal Extract
  • Antiseptic Solution
  • Iodine Solution
  • Hydrogen Peroxide
  • Eye Drops
  • Nasal Spray
  • Medical Alcohol
  • Saline Solution
  • Disinfection Spray

Customer Pain Points

Problem with Pharma & Healthcare Filling and Packaging Industry

Compliance and GMP Control Challenges.

1. Manual operation poses a high risk of contamination and is difficult to meet the requirements of a sterile and clean environment.
Oral solid preparations and sterile preparations (injections, eye drops, freeze-dried powders) have strict cleanliness level requirements for the production environment and operation process.
When manual packing is involved, factors such as hair, dander, microorganisms of the personnel, as well as inadequate hand disinfection and improper dressing, may all cause product contamination.
Once sterile drugs are contaminated, it will directly lead to serious medical safety incidents, and at the same time violate GMP regulations, resulting in production suspension, revocation of qualifications, and huge penalties.

2. The sealing performance and integrity of the packing cannot be reliably guaranteed.
The sealing performance and integrity of the packaging cannot be reliably guaranteed.
The sealing performance of drug packaging is directly related to product stability, moisture prevention, oxidation prevention and pollution prevention.
This applies to the sealing of oral liquids and eye drops, as well as ointment tubes and heat-sealed blister packs. Manual or semi-automatic equipment is prone to sealing problems such as insufficient sealing, false sealing, damage and cracking. These problems can lead to drugs absorbing moisture, deteriorating and losing their efficacy.
Defects in sealing are considered serious quality accidents, especially for injection drugs and sterile preparations.

3. The protective ability and compatibility of packaging materials with drugs is insufficient.
Some drugs are sensitive to light, oxygen and humidity.
If you don't handle the packaging materials properly when you're packing them, they can get scratched or damaged. This can stop them from protecting the drugs from light and moisture, which can make the drugs go bad or be less effective.

4. Manual inspection is highly subjective and has a high rate of missed detections.
Relying on manual visual inspection for aspects such as the appearance of the medicine, blister mold formation, dosage, sealing performance, and label integrity is greatly affected by fatigue, attention, and experience. This leads to a high rate of missed detections and misjudgements, meaning that unqualified products cannot be completely intercepted. There is a risk of them entering the market.

Production Efficiency and Flexibility Issues.

1. Production process is fragmented and involves a lot of manual handling. There is aclear bottleneck in production capacity.
Pharmaceutical packaging is a lengthy process involving several different operations for solid preparations.
These include bottle sorting, filling, sealing, capping, aluminium foil sealing, labelling, box packing, placing instructions, sealing boxes, wrapping and boxing. For bubble packaging, the process involves bubble mould forming, filling, heat sealing, printing the batch number, and box packing.
These manual, segmented operations and multiple transfers result in low efficiency and increase the risk of contamination and confusion. They also cannot match the production capacity of the front-end stages of granulation, tablet pressing and liquid preparation, thus becoming the bottleneck of the entire production line.

2. Multiple product varieties and small-batch production, along with complex and timeconsuming line changes.
Pharmaceutical companies generally have multiple product varieties, specifications and dosage forms in circulation simultaneously.
Line changes are particularly common for generic drugs, common drugs, paediatric medications and customised drugs. Traditional equipment line changes require the manual replacement of moulds, adjustment of parameters, cleaning of equipment and verification of status. This makes the line change process long and difficult, prone to cross-contamination, and results in low equipment utilisation rates.

Cost Control and Management

1. Compliance costs and rework costs are extremely high.
When drugs have packing deviations, contamination, incorrect labelling or confusion, the entire batch must be reworked, scrapped or recalled.
Costs of materials, production, testing and logistics are also extremely high.
Risks of regulatory penalties and damage to brand reputation.

2. High material loss and cleaning costs.
Manual operating errors result in medicine bottles, blister sheets, labels and packing boxes being scrapped, and significant material waste occurs during line changes and cleaning processes.
Furthermore, the cleaning, disinfection and verification procedures in the clean area are cumbersome, time-consuming and labour-intensive.

3. Production data is not transparent, and precise management is lacking.
Manual statistics of output, qualification rate, consumable usage and equipment status result in inaccurate, non-real-time data. This makes it impossible to optimise production capacity, conduct cost accounting or perform preventive maintenance on equipment. Management relies on experience, which makes it difficult to achieve lean production.

Technical Highlights & Solutions

Why choose TRPACK as your pharma & healthcare filling packaging partner?

Entire process is fully enclosed and automated, which reduces the risk of contamination

Automatic packaging production line is made of 316L stainless steel, food and pharmaceutical-grade rubber and plastic, and features easy cleaning and no dead corners. It can be adapted for use in D-, C- and B-class clean workshops. Some sterile preparations can be paired with A-class laminar flow modules.
The entire line uses enclosed transportation and isolated operations to significantly reduce direct contact between personnel and drugs. This reduces the risk of microbial and particulate contamination at source, meeting the GMP clean requirements for sterile drugs and oral preparations.

Prevent confusion. Design for elimination of human errors

The system is equipped with scanning, error prevention and specification identification functions, as well as batch verification. During the bottle sorting, filling, carton packing and boxing stages, the names, specifications, batch numbers and packing materials of the drugs are scanned and verified. If there is any mismatch, the machine will immediately stop and sound an alarm. This ensures that batch confusion, incorrect packing and packing omissions are completely prevented from a hardware perspective.

Identification is precise and fully traceable throughout the process

Online inkjet printing, laser marking, labelling and coding systems are integrated alongside visual inspection to ensure that batch numbers, expiry dates, electronic supervision codes and anti- ounterfeiting codes are clear, complete and precisely positioned.
The production line can be connected to MES, WMS and ERP systems to automatically collect and store production time, equipment parameters, batch information, material information, quality inspection results, operator information and environmental data. This forms a complete electronic batch record and enables full traceability of the smallest sales unit, meeting the regulatory traceability requirements of domestic drug supervision, the FDA and EU GMP. 

Automated record keeping ensures that compliance audits are trouble-free

The system automatically generates electronic batch production records, equipment operation logs and deviation alarm records. This unalterable, auditable and exportable data fully meets the GMP requirements for documents and records, significantly reducing the risk of surprise inspections and audits.

High-precision, high-consistency sealing and moulding

Specialized workstations are configured for different dosage forms. Oral liquids and eye drops use servo cap screwing and electromagnetic induction aluminium foil sealing with constant torque and reliable sealing. Ointments and gels use ultrasonic/hot air tail sealing/folding tail processing with tight sealing, which fundamentally solves the problems of drug leakage, moisture absorption and contamination.

Extensive Project Experience

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